The correct option is 1, 2, and 3 because genome sequencing provides valuable insights into the genetic makeup of crops, enabling the identification of genetic markers for critical traits such as disease resistance and drought tolerance (1). This molecular understanding facilitates the accelerated development of new crop varieties through targeted breeding programs, significantly reducing the time involved in traditional methods (2). Additionally, by elucidating the genetic relationships between hosts and pathogens, genome sequencing can aid in devising effective strategies for disease management in agriculture (3). Thus, it serves as a powerful tool for enhancing agricultural productivity and sustainability in India.