The correct option is "1 and 2 only" because Pneumococcal Conjugate Vaccines (PCVs) provide broad protection against serious infections caused by Streptococcus pneumoniae, including pneumonia, meningitis, and sepsis, which are significant health concerns in India, particularly among children. Additionally, by effectively immunizing populations against these diseases, reliance on antibiotics can be decreased, helping to combat the rising issue of antibiotic resistance, which poses a major challenge to public health. However, the statement that these vaccines have no side effects is inaccurate; like any vaccine, they can have side effects, even if they are generally mild and manageable.